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Nakamura, Yusuke
One or more keywords matched the following items that are connected to Nakamura, Yusuke
Item TypeName
Concept Protein Kinase Inhibitors
Academic Article MELK inhibitor, novel molecular targeted therapeutics for human cancer stem cells.
Academic Article Development of an orally-administrative MELK-targeting inhibitor that suppresses the growth of various types of human cancer.
Academic Article A unique hinge binder of extremely selective aminopyridine-based Mps1 (TTK) kinase inhibitors with cellular activity.
Academic Article VAV3 mediates resistance to breast cancer endocrine therapy.
Academic Article TOPK inhibitor induces complete tumor regression in xenograft models of human cancer through inhibition of cytokinesis.
Academic Article T-LAK cell-originated protein kinase presents a novel therapeutic target in FLT3-ITD mutated acute myeloid leukemia.
Academic Article Discovery of imidazo[1,2-b]pyridazine derivatives: selective and orally available Mps1 (TTK) kinase inhibitors exhibiting remarkable antiproliferative activity.
Academic Article Afatinib Activity in Platinum-Refractory Metastatic Urothelial Carcinoma in Patients With ERBB Alterations.
Academic Article Oncogenic roles of TOPK and MELK, and effective growth suppression by small molecular inhibitors in kidney cancer cells.
Academic Article Preclinical evaluation of biomarkers associated with antitumor activity of MELK inhibitor.
Academic Article Anti-myeloma activity of MELK inhibitor OTS167: effects on drug-resistant myeloma cells and putative myeloma stem cell replenishment of malignant plasma cells.
Academic Article T-LAK Cell-Originated Protein Kinase (TOPK) as a Prognostic Factor and a Potential Therapeutic Target in Ovarian Cancer.
Academic Article WHSC1L1-mediated EGFR mono-methylation enhances the cytoplasmic and nuclear oncogenic activity of EGFR in head and neck cancer.
Academic Article Potent anti-myeloma activity of the TOPK inhibitor OTS514 in pre-clinical models.
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  • Protein Kinase Inhibitors